The CTDSP1 antibody from MyBioSource.com is a Mouse Monoclonal antibody to CTDSP1. This antibody recognizes Human antigen. The CTDSP1 antibody has been validated for the following applications: Western Blot.
Description
Mouse monoclonal CTDSP1 antibody
Carboxy-terminal domain, RNA polymerase II, polypeptide A phosphatase 1, also known as CTDSP1, is a class 2C phosphatase with activity dependent on the conserved DxD motif. CTDSP1 preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Also it negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation